Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946663 | 1.00 | ATM (0.33) | ATMMEN1TSHRKMT2ANPC1 | |
| SCHEMBL8946658 | 1.00 | ATM (0.33) | ATMMEN1TSHRKMT2ANPC1 | |
| SCHEMBL8946539 | 0.76 | HTR2A (0.36) | MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8946545 | 0.76 | HTR2A (0.36) | MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8946537 | 0.76 | HTR2A (0.36) | MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8946736 | 0.70 | HTR2A (0.33) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8946738 | 0.70 | HTR2A (0.33) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8946661 | 0.68 | MAOA (0.32) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8946653 | 0.68 | MAOA (0.32) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8946657 | 0.68 | MAOA (0.32) | MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |