Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946736 | 0.77 | HTR2A (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946739 | 0.77 | HTR2A (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946738 | 0.77 | HTR2A (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946707 | 0.72 | S100B (0.35) | S100B | |
| SCHEMBL8946687 | 0.72 | ALDH1A1 (0.36) | S100BMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946675 | 0.72 | ALDH1A1 (0.36) | S100BMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946711 | 0.68 | S100B (0.33) | S100BMEN1KMT2A | |
| SCHEMBL8946706 | 0.68 | S100B (0.33) | S100BMEN1KMT2A | |
| SCHEMBL8946758 | 0.67 | HTR2A (0.37) | MEN1KMT2A | |
| SCHEMBL8946755 | 0.67 | HTR2A (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |