Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946929 | 0.74 | MAPT (0.40) | CHRNA7HTR3AACHEDYRK1A | |
| SCHEMBL6954549 | 0.71 | CHRNA7 (0.39) | HTR2CHTR2BHTR2ACHRNA7HTR3A | |
| SCHEMBL6954250 | 0.71 | HTR2A (0.43) | HTR2CHTR2BHTR2ACHRNA7HTR3A | |
| SCHEMBL3911097 | 0.71 | HTR3A (0.49) | CHRNA7HTR3ANCF1 | |
| SCHEMBL8187347 | 0.70 | NCF1 (0.45) | HTR2CHTR2BHTR2ACHRNA7HTR3A | |
| Water SCHEMBL6958984 | 0.70 | HTR3A (0.48) | CHRNA7HTR3ANCF1 | |
| Hydrochloric Acid SCHEMBL6949333 | 0.70 | NCF1 (0.45) | HTR2CHTR2BHTR2ACHRNA7HTR3A | |
| SCHEMBL7753896 | 0.67 | CHRNB2 (0.50) | HTR2BHTR3ANCF1DYRK1A | |
| SCHEMBL2709277 | 0.62 | NCF1 (0.54) | HTR3ANCF1 | |
| SCHEMBL1536638 | 0.61 | KDM4E (0.47) | CHRNA7HTR3AACHEDYRK1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580982-A | ANTIDEPRESSANTS; ANTICHOLINERGIC AGENTS; ALZHEIMER'S DISEASE; AMINE OXIDASE INHIBITORS | HOECHST MARION ROUSSEL INC. (US) | 1996-12-03 | — | — | US | disclosed |