Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947196 | 0.86 | KDM4E (0.45) | KDM4ELMNAPOLBPKMMAPT | |
| SCHEMBL26113894 | 0.80 | SMN1; SMN2 (0.49) | HTR2CSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL14609981 | 0.76 | SMN1; SMN2 (0.54) | HTR2CSMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL8162245 | 0.74 | CYP2C19 (0.44) | SMN1; SMN2CYP2C19 | |
| SCHEMBL8172630 | 0.74 | CYP2C19 (0.44) | SMN1; SMN2CYP2C19 | |
| SCHEMBL5118035 | 0.74 | SMN1; SMN2 (0.50) | HTR2CSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL31722609 | 0.74 | MEN1 (0.52) | POLBSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7581386 | 0.73 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL31252092 | 0.72 | ALDH1A1 (0.49) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL978529 | 0.72 | SMN1; SMN2 (0.47) | HTR2CPOLBSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561149-A | FOR NASAL ADMINISTRATION | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |