Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946980 | 0.86 | HTR2C (0.43) | KDM4ESIGMAR1POLBPKMLMNA | |
| SCHEMBL11345558 | 0.74 | LMNA (0.39) | KDM4ESIGMAR1POLBPKMLMNA | |
| SCHEMBL4591916 | 0.72 | KDM4E (0.43) | KDM4EPOLBPKMLMNAMAPT | |
| SCHEMBL25566966 | 0.72 | CYP2D6 (0.42) | SIGMAR1ALDH1A1CYP2D6 | |
| SCHEMBL3250253 | 0.72 | OPRK1 (0.51) | SIGMAR1POLBALDH1A1 | |
| SCHEMBL3247032 | 0.72 | OPRK1 (0.51) | SIGMAR1POLBALDH1A1 | |
| SCHEMBL8912102 | 0.71 | USP2 (0.40) | KDM4EPOLBPKMLMNAMAPT | |
| SCHEMBL2206046 | 0.71 | SIGMAR1 (0.59) | SIGMAR1POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL4123527 | 0.70 | SIGMAR1 (0.58) | SIGMAR1POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL485328 | 0.70 | SIGMAR1 (0.55) | KDM4ESIGMAR1POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561149-A | FOR NASAL ADMINISTRATION | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |