Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947128 | 0.75 | MAPK1 (0.53) | POLBHPGDCYP1A2CYP2C9CYP2C19 | |
| Tazanolast SCHEMBL28495 | 0.75 | HPGD (0.45) | MAPTHPGDRAB9ACYP1A2CYP2C9 | |
| SCHEMBL8947294 | 0.74 | MAPK1 (0.61) | POLBHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8947360 | 0.73 | ALDH1A1 (0.52) | HPGDRAB9ACYP1A2CYP2C9CYP2C19 | |
| Tazanolast SCHEMBL1651344 | 0.72 | MAPT (0.61) | MAPTPOLBHPGDRAB9ACYP2C9 | |
| SCHEMBL8118104 | 0.71 | MAPK1 (0.53) | MAPTPOLBHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL8947277 | 0.70 | TRPV1 (0.50) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11647389 | 0.70 | HPGD (0.76) | MAPTHPGDRAB9ACYP1A2CYP2C9 | |
| SCHEMBL8947184 | 0.70 | LMNA (0.48) | HPGDCYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL9568775 | 0.69 | NPSR1 (0.50) | MAPTHPGDMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35281-E | ANTIDIABETIC AGENTS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0388967-B1 | Aldose reductase inhibitor | WAKAMOTO PHARMA CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5055481-A | Alleviate diabetic complications | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0388967-A1 | Aldose reductase inhibitor | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1990-09-26 | — | — | EP | disclosed |