Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794443 | 0.89 | ALDH1A1 (0.55) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL5048632 | 0.80 | GRIA2 (0.67) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| Gyki-52466 SCHEMBL29357520 | 0.74 | GRIA2 (1.00) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| Gyki-52466 SCHEMBL194854 | 0.74 | GRIA2 (1.00) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| Gyki-52466 SCHEMBL25227675 | 0.73 | LMNA (1.00) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| Gyki-52466 SCHEMBL249675 | 0.73 | LMNA (1.00) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| Gyki-52466 SCHEMBL29651319 | 0.73 | LMNA (1.00) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL7398670 | 0.72 | MAPT (0.66) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10887479 | 0.71 | GRIA2 (0.76) | GRIA2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL8792742 | 0.69 | ALDH1A1 (0.64) | GRIA2MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521174-A | ANTISPASMODIC AGENTS | GYOGYSZERKUTATO INTEZET KV. (HU) | 1996-05-28 | — | — | US | disclosed |