SCHEMBL8947827

SCHEMBL8947827

CC(C#N)N(C)c1ccc(C=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.52
CYP2A13 Q16696 1/20 0.52
ALDH1A1 P00352 6/20 0.44
ALDH1A3 P47895 2/20 0.44
ALDH3A1 P30838 1/20 0.44
TYR P14679 1/20 0.42
EGFR P00533 2/20 0.39
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
HSD17B10 Q99714 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11695977 0.84 CYP2A6 (0.48) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL10939019 0.79 ALDH1A1 (0.50) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL11699062 0.78 CYP2A6 (0.43) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL14387478 0.76 MEN1 (0.57) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL11696293 0.76 ALDH1A3 (0.46) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL10936125 0.76 CYP2A6 (0.57) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL28631807 0.76 APP (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL1568079 0.76 CYP2A6 (0.57) CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1
SCHEMBL11580322 0.76 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2059899 0.75 MAOB (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5582621-A Bulk dyeing of plastics BAYER AKTIENGESELLSCHAFT (DE) 1996-12-10 US disclosed
EP-0703270-A2 Mass colouring of plastics BAYER AG (DE) 1996-03-27 EP disclosed
US-4542224-A Process for preparing cationic methine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-09-17 US disclosed
EP-0074569-B1 CATIONIC METHINE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE, IN DYEING TEXTILE MATERIALS AND OTHER SUBSTRATES BAYER AG (DE) 1985-06-19 EP disclosed
US-4513142-A Preparation of cationic methine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-04-23 US disclosed
EP-0074569-A2 Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates BAYER AG (DE) 1983-03-23 EP disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed