SCHEMBL11696293

SCHEMBL11696293

CCCN(c1ccc(C=O)cc1)C(C)C#N

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 5/20 0.46
ALDH3A1 P30838 4/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP2A6 P11509 2/20 0.41
CYP2A13 Q16696 1/20 0.41
TYR P14679 1/20 0.37
EGFR P00533 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10939019 0.89 ALDH1A1 (0.50) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11693861 0.82 ALDH1A1 (0.37) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11695977 0.80 CYP2A6 (0.48) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11702180 0.79 KCNN4 (0.38) ALDH1A1MEN1MAPTKMT2ANPSR1
SCHEMBL8947827 0.76 CYP2A6 (0.52) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11699062 0.75 CYP2A6 (0.43) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL14939969 0.73 ALDH1A1 (0.59) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11698905 0.72 ALDH1A1 (0.39) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL1607796 0.71 ALDH3A1 (0.73) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13
SCHEMBL11696300 0.71 ALDH3A1 (0.56) ALDH1A3ALDH3A1ALDH1A1CYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002616-A POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-11 US disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed