Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947866 | 0.85 | SIGMAR1 (0.56) | SIGMAR1TMEM97 | |
| SCHEMBL8947838 | 0.85 | SIGMAR1 (0.56) | SIGMAR1TMEM97 | |
| SCHEMBL8947787 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97 | |
| SCHEMBL7397638 | 0.78 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL7394691 | 0.78 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL8948005 | 0.78 | TMEM97 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL8948029 | 0.78 | SIGMAR1 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL8110473 | 0.78 | SIGMAR1 (1.00) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7497970 | 0.77 | SIGMAR1 (0.67) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7502034 | 0.77 | SIGMAR1 (0.67) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0613898-A1 | Aryl or arylalkyl-carbonyl heterocyclic derivatives, processes for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | disclosed |