Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947866 | 0.91 | SIGMAR1 (0.56) | TMEM97SIGMAR1 | |
| SCHEMBL8947838 | 0.89 | SIGMAR1 (0.56) | TMEM97SIGMAR1 | |
| SCHEMBL8948078 | 0.89 | HTR2A (0.55) | TMEM97SIGMAR1 | |
| SCHEMBL8947898 | 0.88 | HTR2A (0.55) | SIGMAR1 | |
| SCHEMBL8947935 | 0.83 | HTR2A (0.59) | TMEM97SIGMAR1 | |
| SCHEMBL8947787 | 0.82 | SIGMAR1 (0.58) | TMEM97SIGMAR1 | |
| SCHEMBL8947883 | 0.82 | SIGMAR1 (0.46) | TMEM97SIGMAR1 | |
| SCHEMBL8947902 | 0.81 | KCNH2 (0.53) | TMEM97SIGMAR1 | |
| SCHEMBL8948106 | 0.81 | HTR2A (0.49) | SIGMAR1 | |
| SCHEMBL8948101 | 0.81 | TMEM97 (0.49) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0613898-A1 | Aryl or arylalkyl-carbonyl heterocyclic derivatives, processes for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | disclosed |