Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.69 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947762 | 0.89 | HTR1A (0.66) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948076 | 0.83 | HTR1A (0.64) | HTR1AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL9449598 | 0.82 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8948137 | 0.81 | HTR1A (0.70) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8947985 | 0.78 | KDM4E (0.58) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8947779 | 0.76 | KDM4E (0.54) | HTR1AHTR2CSIGMAR1TMEM97HTR7 | |
| Hydrochloric Acid SCHEMBL9437971 | 0.76 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948104 | 0.74 | HTR2A (0.52) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL9449853 | 0.73 | HTR1A (0.86) | HTR1AHTR2CSIGMAR1TMEM97 | |
| SCHEMBL8947948 | 0.73 | HTR1A (1.00) | HTR1AHTR2CSIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | claimed |