Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.70 |
| ▸ | HTR2C | P28335 | 5/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 4/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947933 | 0.88 | HTR1A (0.66) | HTR1AHTR2CHTR7 | |
| SCHEMBL8948192 | 0.83 | HTR1A (0.65) | HTR1AHTR2CHTR7 | |
| SCHEMBL8948062 | 0.81 | HTR1A (0.69) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8948013 | 0.81 | HTR1A (0.56) | HTR1AHTR2CHTR7 | |
| SCHEMBL7761659 | 0.80 | HTR1A (1.00) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8948074 | 0.79 | HTR1A (0.53) | HTR1AHTR2CSIGMAR1HTR7 | |
| SCHEMBL8947994 | 0.77 | CYP1A2 (0.51) | HTR1AHTR2CSIGMAR1HTR7SLC6A4 | |
| SCHEMBL8110473 | 0.77 | SIGMAR1 (1.00) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948014 | 0.77 | HTR1A (0.52) | HTR1AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL9449678 | 0.76 | HTR1A (0.98) | HTR1AHTR2CSIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | claimed |