Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393870 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL19513025 | 0.88 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10392904 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8787295 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL14741026 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9684618 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8541265 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9367537 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5171751 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL474056 | 0.81 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0613898-A1 | Aryl or arylalkyl-carbonyl heterocyclic derivatives, processes for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | disclosed |
| US-4558060-A | HYPNOTIC PROPERTIES; ANTI-HEART FAILURE MEDICINE | RIOM LABORATORIES - CERM S.A. (FR) | 1985-12-10 | — | — | US | disclosed |