Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14741026 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL10393870 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL8541265 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL9367537 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL10392904 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL8787295 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL8948117 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL23123120 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL474056 | 0.82 | ALDH1A1 (0.73) | ALDH1A1HPGDKMT2AMEN1TP53 | |
| SCHEMBL23123168 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |