SCHEMBL8948161

SCHEMBL8948161

CC(=O)/C=C/C1CCCCC1C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.38
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948168 1.00 EPHX1 (0.38) EPHX1TAS1R3TAS1R1CA1CA2
SCHEMBL2688800 0.83 EPHX1 (0.38) EPHX1TAS1R3TAS1R1CA1CA2
SCHEMBL12842511 0.81 EPHX1 (0.33) EPHX1TAS1R3TAS1R1CA1CA2
SCHEMBL2220502 0.79 UGT2B7 (0.34) EPHX1TAS1R3TAS1R1CA1CA2
SCHEMBL10151521 0.76 TAS1R3 (0.34) EPHX1TAS1R3TAS1R1
SCHEMBL31356724 0.73 PTPN2 (0.35) PTPN2PTPN1
SCHEMBL14142775 0.73 CA1 (0.40) EPHX1CA1CA2CA4
SCHEMBL809692 0.71 CES2 (0.35) EPHX1PTPN2PTPN1
SCHEMBL814591 0.71 CES2 (0.35) EPHX1PTPN2PTPN1
SCHEMBL26090607 0.70 CA1 (0.36) EPHX1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484949-A Method for the synthesis of α β-unsaturated ketones NIPPON SODA CO., LTD. (JP) 1996-01-16 US disclosed
EP-0454867-A1 A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. NIPPON SODA CO (JP) 1991-11-06 EP disclosed
WO-1991007370-A1 A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES NIPPON SODA CO., LTD. (JP) 1991-05-30 WO disclosed