Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809692 | 1.00 | CES2 (0.35) | CES2CES1GRIN1GRIN2BPTPN2 | |
| SCHEMBL31356724 | 0.98 | PTPN2 (0.35) | CES2CES1GRIN1GRIN2BPTPN2 | |
| SCHEMBL10615509 | 0.93 | — | — | |
| SCHEMBL10615513 | 0.93 | — | — | |
| SCHEMBL319121 | 0.87 | — | — | |
| SCHEMBL319122 | 0.87 | — | — | |
| SCHEMBL13604712 | 0.85 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL13604716 | 0.83 | CES2 (0.30) | CES2CES1 | |
| SCHEMBL28480462 | 0.82 | GRIN1 (0.33) | CES2CES1GRIN1GRIN2BPADI4 | |
| SCHEMBL761935 | 0.80 | CES2 (0.38) | CES2CES1GRIN1GRIN2BPADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528983-A | Method for green catalytic synthesis of gamma-ketophosphine oxide by asymmetric alkylaluminum compound | 北京理工大学 | 2025-02-28 | — | — | CN | disclosed |
| EP-3930849-B1 | THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250043211-A1 | 4-CYCLOHEXYLBUTAN-2-ONE AS A FRAGRANCE | SYMRISE AG (DE) | 2025-02-06 | — | — | US | disclosed |
| EP-4444838-A1 | 4-CYCLOHEXYLBUTAN-2-ONE AS A FRAGRANCE | Symrise AG (DE) | 2024-10-16 | — | — | EP | disclosed |
| US-12114681-B2 | Fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-10-15 | — | — | US | disclosed |
| CN-118574918-A | 4-Cyclohexylbutan-2-one as a fragrance | 西姆莱斯股份公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023104308-A1 | 4-CYCLOHEXYLBUTAN-2-ONE AS A FRAGRANCE | SYMRISE AG (DE) | 2023-06-15 | — | — | WO | disclosed |
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
| CN-113993587-A | Thiazole derivatives as protein secretion inhibitors | 科智生命科学公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20210227864-A1 | FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-29 | — | — | US | disclosed |
| EP-0195053-B1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0124041-B2 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF CYCLOHEXANE DIONE | BASF Aktiengesellschaft (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0454867-A1 | A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. | NIPPON SODA CO (JP) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007370-A1 | A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| WO-1990003113-A1 | ATTRACTANCE FOR DACUS LATIFRONS, THE MALAYSIAN FRUIT FLY | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1990-04-05 | — | — | WO | disclosed |
| US-4877607-A | CYCLOHEXYL AND CYCLOHEXENYL ALIPHATIC ALCOHOLS AND KETONES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0195053-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR. | CHEVRON RES & TECH (US) | 1986-09-24 | — | — | EP | disclosed |
| WO-1986002065-A1 | PROCESS FOR PREPARING 1,3-CYCLOHEXANEDIONE DERIVATIVES AND INTERMEDIATES THEREFOR | CHEVRON RESEARCH COMPANY (US) | 1986-04-10 | — | — | WO | disclosed |
| EP-0124041-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF CYCLOHEXANE DIONE | BASF Aktiengesellschaft (DE) | 1985-11-21 | — | — | EP | disclosed |
| EP-0124041-A1 | Process for the preparation of derivatives of cyclohexane dione | BASF Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | CES2 3680/4885CES1 1087/4885GRIN1 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.