Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10481229 | 0.98 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL16042547 | 0.74 | L3MBTL1 (0.44) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL10481230 | 0.72 | HTR2B (0.40) | ALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL30720219 | 0.66 | LMNA (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL9110788 | 0.66 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL212999 | 0.66 | LMNA (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL19030643 | 0.66 | KDM4E (0.40) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL926329 | 0.65 | L3MBTL1 (0.67) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL2767291 | 0.65 | LMNA (0.53) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL453951 | 0.63 | GAA (0.68) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| US-5032137-A | Hair dye | L'OREAL (FR) | 1991-07-16 | — | — | US | disclosed |
| US-4979961-A | p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process | L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | disclosed |