Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.45 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.44 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159482 | 0.92 | MAPK1 (0.53) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL8948318 | 0.87 | TDP1 (0.48) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL4411410 | 0.80 | ALDH1A1 (0.67) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL16217241 | 0.77 | TDP1 (0.38) | KMT2AMEN1TDP1NPC1MAPK1 | |
| Formamide SCHEMBL28861985 | 0.74 | ALDH1A1 (0.55) | KMT2AMEN1TDP1NPC1MAPK1 | |
| Formamide SCHEMBL28861984 | 0.74 | ALDH1A1 (0.55) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL15274139 | 0.71 | MEN1 (1.00) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL243333 | 0.71 | MEN1 (1.00) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL243332 | 0.71 | MEN1 (1.00) | KMT2AMEN1TDP1NPC1MAPK1 | |
| SCHEMBL31073963 | 0.71 | MEN1 (1.00) | KMT2AMEN1TDP1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2015-06-25 | — | — | US | disclosed |
| US-8932370-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-8932370-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-01-16 | — | — | US | disclosed |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-01-16 | — | — | US | disclosed |
| US-8444715-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-8444715-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120272990-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120272990-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| US-8187340-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8187340-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120272990-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KMT2A 1622/4885MEN1 3187/4885TDP1 841/4885 |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KMT2A 1622/4885MEN1 3187/4885TDP1 841/4885 |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KMT2A 1622/4885MEN1 3187/4885TDP1 841/4885 |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KMT2A 1622/4885MEN1 3187/4885TDP1 841/4885 |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KMT2A 1622/4885MEN1 3187/4885TDP1 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.