Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307975 | 0.83 | MAPT (0.40) | GAA | |
| SCHEMBL17907572 | 0.83 | NPC1 (0.42) | PTPN1CA1CA2TRPV1 | |
| SCHEMBL6754862 | 0.83 | MAPK1 (0.46) | GAA | |
| SCHEMBL43876 | 0.81 | ALDH1A1 (0.49) | — | |
| SCHEMBL10810727 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL15515208 | 0.81 | ELANE (0.46) | GAA | |
| SCHEMBL6887250 | 0.80 | ESR1 (0.48) | PTPN1CA1CA2RXRA | |
| Hydrochloric Acid SCHEMBL7910400 | 0.80 | GAA (0.37) | CA1CA2GAA | |
| Hydrochloric Acid SCHEMBL7910501 | 0.80 | GAA (0.37) | CA1CA2GAA | |
| SCHEMBL5983433 | 0.80 | GAA (0.31) | CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |
| US-5290937-A | Radiolabeling of proteins using alkoxyphenol derivatives | E. R. SQUIBB & SONS, INC. (US) | 1994-03-01 | — | — | US | disclosed |