Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | PCNA | P12004 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553046 | 0.81 | HSD17B2 (0.56) | POLBSMN1; SMN2CYP1A2HSD17B2KDM4E | |
| SCHEMBL8948561 | 0.80 | TPMT (0.38) | CA1CA2PTPN1RXRA | |
| SCHEMBL6307975 | 0.74 | MAPT (0.40) | POLBLMNAHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL17907572 | 0.74 | NPC1 (0.42) | CA1CA2MAPK1PTPN1LMNA | |
| SCHEMBL6754862 | 0.73 | MAPK1 (0.46) | POLBHIF1AMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7129075 | 0.72 | ESR1 (0.45) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL43876 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL15515208 | 0.72 | ELANE (0.46) | POLBHIF1AMAPK1LMNAHPGD | |
| SCHEMBL10810727 | 0.72 | ALDH1A1 (0.39) | MAPK1ALDH1A1 | |
| SCHEMBL16871705 | 0.72 | PTPN2 (0.41) | PTPN1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087733-A2 | PREVENTION AND TREATMENT OF ALZHEIMER AMYLOID DEPOSITION | NEW YORK UNIVERSITY (US) | 2004-10-14 | — | — | WO | disclosed |