Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047980 | 0.83 | LOXL2 (0.33) | — | |
| SCHEMBL6307975 | 0.83 | MAPT (0.40) | GAAMAPT | |
| SCHEMBL9753847 | 0.81 | LMNA (0.35) | GAAMAPTESR1 | |
| SCHEMBL8948561 | 0.80 | TPMT (0.38) | GAACA1CA2 | |
| SCHEMBL17907572 | 0.80 | NPC1 (0.42) | MAPTCA1CA2 | |
| SCHEMBL6754862 | 0.79 | MAPK1 (0.46) | GAAMAPT | |
| SCHEMBL43876 | 0.77 | ALDH1A1 (0.49) | MAPT | |
| SCHEMBL15515208 | 0.77 | ELANE (0.46) | GAAMAPT | |
| SCHEMBL10810727 | 0.77 | ALDH1A1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7910400 | 0.76 | GAA (0.37) | GAAMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641818-A1 | POLYPEPTIDES HAVING BINDING AFFINITY FOR HER2 | Affibody AB (SE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005003156-A1 | POLYPEPTIDES HAVING BINDING AFFINITY FOR HER2 | AFFIBODY AB (SE) | 2005-01-13 | — | — | WO | disclosed |