SCHEMBL8948577

SCHEMBL8948577

O=C=NC1Oc2cccc(Cl)c2C1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.32
GUSB P08236 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6704023 0.73 TTR (0.36) TTRGUSBCES1
SCHEMBL6905176 0.67 MAOA (0.33)
SCHEMBL9522618 0.60 CA2 (0.33)
SCHEMBL259172 0.57 CES1 (0.36) GUSBCES1
SCHEMBL259173 0.57 CES1 (0.36) GUSBCES1
SCHEMBL9780105 0.57 TSHR (0.40) TTRCES1
SCHEMBL2471569 0.56 TSHR (0.57) CES1
SCHEMBL8809006 0.56 PBRM1 (0.36) CES1
SCHEMBL4496746 0.56 PBRM1 (0.39) CES1
SCHEMBL29274153 0.56 PBRM1 (0.39) CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed
WO-1995005079-A1 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS FMC CORPORATION (US) 1995-02-23 WO disclosed