Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948710 | 0.90 | SIGMAR1 (0.43) | SIGMAR1ITGB3ITGA2BF10GRM2 | |
| SCHEMBL8948664 | 0.89 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BF10GRM2 | |
| SCHEMBL8311319 | 0.89 | SIGMAR1 (0.42) | SIGMAR1ITGB3ITGA2BF10GRM2 | |
| SCHEMBL8948609 | 0.87 | ITGB3 (0.48) | SIGMAR1ITGB3ITGA2BF10F2 | |
| SCHEMBL8948674 | 0.86 | GRM2 (0.46) | SIGMAR1GRM2 | |
| SCHEMBL8311318 | 0.83 | F10 (0.49) | SIGMAR1ITGB3ITGA2BF10GRM2 | |
| SCHEMBL8316871 | 0.80 | SIGMAR1 (0.49) | SIGMAR1F10GRM2 | |
| SCHEMBL8310716 | 0.80 | SIGMAR1 (0.49) | SIGMAR1F10GRM2 | |
| SCHEMBL8948597 | 0.80 | SIGMAR1 (0.40) | SIGMAR1ITGB3ITGA2BF10GRM2 | |
| SCHEMBL8316462 | 0.79 | SIGMAR1 (0.46) | SIGMAR1ITGB3ITGA2BF10GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |