Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948664 | 0.91 | SIGMAR1 (0.45) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8948593 | 0.90 | SIGMAR1 (0.41) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8948777 | 0.87 | ITGB3 (0.51) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8948685 | 0.85 | ITGB3 (0.48) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8948845 | 0.84 | GRM2 (0.51) | SIGMAR1GRM2 | |
| SCHEMBL8316400 | 0.81 | ITGB3 (0.50) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8316462 | 0.80 | SIGMAR1 (0.46) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8310904 | 0.80 | SIGMAR1 (0.46) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8312579 | 0.80 | SIGMAR1 (0.46) | SIGMAR1GRM2ITGB3ITGA2BF10 | |
| SCHEMBL8948703 | 0.80 | SIGMAR1 (0.36) | SIGMAR1GRM2ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |