Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948544 | 0.87 | GRM2 (0.43) | GRM2SIGMAR1 | |
| SCHEMBL8948778 | 0.82 | GRM2 (0.45) | GRM2SIGMAR1CHRM4 | |
| SCHEMBL8948768 | 0.80 | GRM2 (0.47) | GRM2SIGMAR1 | |
| SCHEMBL8316229 | 0.80 | GRM2 (0.51) | GRM2SIGMAR1 | |
| SCHEMBL8948620 | 0.79 | L3MBTL1 (0.44) | GRM2SIGMAR1 | |
| SCHEMBL8948782 | 0.78 | GRM2 (0.47) | GRM2SIGMAR1 | |
| SCHEMBL8458262 | 0.78 | GRM2 (0.42) | GRM2SIGMAR1 | |
| SCHEMBL8948659 | 0.78 | GRM2 (0.48) | GRM2SIGMAR1HRH3 | |
| SCHEMBL8948645 | 0.77 | FKBP1A (0.44) | GRM2 | |
| SCHEMBL8315766 | 0.77 | GRM2 (0.50) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |