Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948713 | 0.88 | GRM2 (0.51) | GRM2SIGMAR1 | |
| SCHEMBL8313964 | 0.83 | GRM2 (0.54) | GRM2SIGMAR1POLB | |
| SCHEMBL8948778 | 0.83 | GRM2 (0.45) | GRM2SIGMAR1NR3C2 | |
| SCHEMBL8948736 | 0.82 | GRM2 (0.48) | GRM2SIGMAR1POLB | |
| SCHEMBL8948884 | 0.81 | GRM2 (0.43) | GRM2SIGMAR1NR3C2 | |
| SCHEMBL8313108 | 0.79 | GRM2 (0.46) | GRM2SIGMAR1 | |
| SCHEMBL8948596 | 0.78 | GRM2 (0.46) | GRM2SIGMAR1 | |
| SCHEMBL8522619 | 0.77 | GRM2 (0.43) | GRM2SIGMAR1POLB | |
| SCHEMBL8948768 | 0.77 | GRM2 (0.47) | GRM2SIGMAR1 | |
| SCHEMBL8948780 | 0.77 | ITGB3 (0.51) | GRM2SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |