Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.49 |
| ▸ | F10 | P00742 | 11/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948691 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8948653 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8948597 | 0.87 | SIGMAR1 (0.40) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8315424 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8948681 | 0.84 | GRM2 (0.47) | SIGMAR1 | |
| SCHEMBL8312934 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8317067 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8315429 | 0.82 | PRSS1 (0.49) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8313893 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BF10PRSS1PRSS2 | |
| SCHEMBL8316123 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BF10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |