Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948849 | 0.90 | GRM2 (0.52) | GRM2SIGMAR1 | |
| SCHEMBL8948770 | 0.89 | GRM2 (0.52) | GRM2SIGMAR1 | |
| SCHEMBL8948597 | 0.86 | SIGMAR1 (0.40) | GRM2SIGMAR1 | |
| SCHEMBL8948743 | 0.84 | GRM2 (0.50) | GRM2SIGMAR1 | |
| SCHEMBL8948612 | 0.84 | ITGB3 (0.49) | SIGMAR1 | |
| SCHEMBL8453566 | 0.82 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948674 | 0.80 | GRM2 (0.46) | GRM2SIGMAR1 | |
| SCHEMBL8948494 | 0.79 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8311049 | 0.79 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8948618 | 0.79 | GRM2 (0.53) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |