Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CD69 | Q07108 | 1/20 | 0.30 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948797 | 0.83 | ATM (0.40) | ATMITGB3ITGA2BCHRM3PTGIR | |
| SCHEMBL8948694 | 0.81 | ITGB3 (0.40) | ATMITGB3ITGA2BCHRM3CHRM2 | |
| SCHEMBL21191260 | 0.79 | ATM (0.39) | ATM | |
| SCHEMBL8948689 | 0.74 | CYP3A4 (0.35) | PDK2ITGB3ITGA2BCHRM3CHRM2 | |
| SCHEMBL20179858 | 0.73 | ITGB3 (0.35) | PDK2ITGB3ITGA2BPTGIR | |
| SCHEMBL20329979 | 0.73 | ATM (0.45) | ATM | |
| SCHEMBL16416415 | 0.72 | ATM (0.46) | ATMPDK2 | |
| SCHEMBL1723069 | 0.71 | ITGB3 (0.33) | PDK2ITGB3ITGA2BPTGIR | |
| SCHEMBL1723072 | 0.71 | PDK2 (0.34) | PDK2ITGB3ITGA2BPTGIR | |
| SCHEMBL20722066 | 0.70 | PDK2 (0.38) | PDK2ITGB3ITGA2BPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |