Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.40 |
| ▸ | PTGIR | P43119 | 7/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312684 | 0.86 | ATM (0.37) | ATMCHRM2CHRM3HRH3 | |
| SCHEMBL12312842 | 0.83 | ATM (0.35) | ATMHRH3 | |
| SCHEMBL8948647 | 0.81 | ATM (0.52) | ITGB3ITGA2BPTGIRATMCHRM2 | |
| SCHEMBL23559355 | 0.80 | SMO (0.42) | ATM | |
| SCHEMBL13858459 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BATM | |
| SCHEMBL8948797 | 0.80 | ATM (0.40) | ITGB3ITGA2BPTGIRATMCHRM3 | |
| SCHEMBL8336494 | 0.79 | ALDH1A1 (0.45) | ITGB3ITGA2BPTGIRCHRM3 | |
| SCHEMBL26751017 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BPTGIR | |
| SCHEMBL23559354 | 0.79 | RAB9A (0.35) | ATM | |
| SCHEMBL23559352 | 0.79 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399681-B2 | Substituted aminothiazolone indazoles as estrogen related receptor-alpha modulators | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-19 | — | — | US | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |