Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948647 | 0.83 | ATM (0.52) | ATMITGB3ITGA2BSMN1; SMN2PTGIR | |
| SCHEMBL8948694 | 0.80 | ITGB3 (0.40) | ATMITGB3ITGA2BKHKPTGIR | |
| SCHEMBL13448667 | 0.79 | SMN1; SMN2 (0.54) | ATMSMN1; SMN2CHRM3CYP3A4CYP2D6 | |
| SCHEMBL26215756 | 0.78 | ATM (0.34) | ATMCHRM3 | |
| SCHEMBL21612876 | 0.77 | MEN1 (0.51) | HSD17B10 | |
| SCHEMBL27406223 | 0.77 | MEN1 (0.51) | HSD17B10 | |
| SCHEMBL9794685 | 0.76 | TAAR1 (0.41) | ITGB3ITGA2BSMN1; SMN2TAAR1LMNA | |
| SCHEMBL8948744 | 0.76 | CYP3A4 (0.51) | TAAR1PTGIRCHRM3CYP1A2CYP3A4 | |
| SCHEMBL7291396 | 0.76 | TAAR1 (0.40) | ITGB3ITGA2BSMN1; SMN2TAAR1PTGIR | |
| SCHEMBL2434662 | 0.74 | ATM (0.69) | ATMSMN1; SMN2CHRM3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |