Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446990 | 0.94 | SIGMAR1 (0.52) | SIGMAR1MEN1TSHRKMT2AABL1 | |
| SCHEMBL8948820 | 0.85 | ALDH1A1 (0.58) | SIGMAR1MEN1TSHRKMT2AACHE | |
| SCHEMBL8948752 | 0.84 | S1PR5 (0.54) | SIGMAR1 | |
| SCHEMBL19450643 | 0.83 | ACHE (0.61) | SIGMAR1MEN1TSHRKMT2AACHE | |
| SCHEMBL5083782 | 0.83 | ATM (0.55) | SIGMAR1MEN1TSHRKMT2AABL1 | |
| Bromide SCHEMBL3141631 | 0.82 | ATM (0.54) | SIGMAR1MEN1TSHRKMT2AABL1 | |
| Hydrochloric Acid SCHEMBL3156656 | 0.82 | ABL1 (0.56) | SIGMAR1MEN1TSHRKMT2AABL1 | |
| SCHEMBL19770184 | 0.81 | ACHE (0.62) | SIGMAR1ABL1RIN1ACHECCR3 | |
| SCHEMBL7651915 | 0.81 | ACHE (0.62) | SIGMAR1ABL1RIN1ACHECCR3 | |
| SCHEMBL11329117 | 0.80 | SIGMAR1 (0.50) | SIGMAR1MEN1TSHRKMT2AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |