Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631931 | 0.85 | MEN1 (0.45) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL8948559 | 0.84 | MAPK1 (0.58) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL8948807 | 0.83 | MEN1 (0.51) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL11631451 | 0.82 | TSHR (0.45) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL11630537 | 0.81 | TSHR (0.44) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL11631680 | 0.81 | MAPK1 (0.58) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL8948809 | 0.79 | TSHR (0.43) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| Iocarmic Acid SCHEMBL38580 | 0.79 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1LMNA | |
| Iosefamic Acid SCHEMBL38639 | 0.78 | TSHR (0.55) | TSHRMAPK1LMNASMN1; SMN2 | |
| Iosefamic Acid SCHEMBL29400390 | 0.78 | TSHR (0.55) | TSHRMAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |