Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948717 | 0.85 | TSHR (0.38) | TSHRKMT2AMAPK1LMNAMAPT | |
| SCHEMBL8948705 | 0.79 | MEN1 (0.56) | TSHRMEN1KMT2AMAPK1LMNA | |
| SCHEMBL8948812 | 0.71 | TSHR (0.43) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8948585 | 0.69 | NLRP3 (0.47) | TSHRMAPK1LMNAALDH1A1KDM4E | |
| SCHEMBL22906082 | 0.68 | SMN1; SMN2 (0.38) | TSHRMEN1KMT2AMAPK1LMNA | |
| SCHEMBL25279991 | 0.68 | TSHR (0.83) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| Ethylene SCHEMBL11220916 | 0.66 | TSHR (0.88) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL50039 | 0.66 | TSHR (1.00) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL28238018 | 0.66 | TSHR (1.00) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29152108 | 0.65 | TSHR (0.68) | TSHRMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |