Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631680 | 0.97 | MAPK1 (0.58) | MAPK1TSHRALDH1A1POLBLMNA | |
| SCHEMBL11630623 | 0.89 | MAPK1 (0.51) | MAPK1TSHRALDH1A1POLBLMNA | |
| SCHEMBL11632892 | 0.89 | MAPK1 (0.48) | MAPK1TSHRALDH1A1POLBLMNA | |
| SCHEMBL11630993 | 0.87 | TSHR (0.52) | MAPK1TSHRALDH1A1TDP1KMT2A | |
| SCHEMBL11637395 | 0.86 | TSHR (0.53) | MAPK1TSHRPOLBLMNAKDM4E | |
| SCHEMBL8948705 | 0.84 | MEN1 (0.56) | MAPK1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL11631270 | 0.82 | MAPK1 (0.45) | MAPK1TSHRALDH1A1POLBLMNA | |
| SCHEMBL11633215 | 0.82 | LMNA (0.71) | MAPK1TSHRALDH1A1POLBLMNA | |
| SCHEMBL9009086 | 0.82 | TSHR (0.53) | MAPK1TSHRLMNAGAA | |
| Iocarmic Acid SCHEMBL38580 | 0.81 | TSHR (0.56) | MAPK1TSHRLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | claimed |
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |