Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449438 | 0.91 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1GRM2FNTA | |
| SCHEMBL8453538 | 0.91 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1GRM2FNTA | |
| SCHEMBL8948759 | 0.91 | SIGMAR1 (0.45) | ITGB3ITGA2BSIGMAR1GRM2FNTA | |
| SCHEMBL8948773 | 0.89 | SIGMAR1 (0.44) | ITGB3ITGA2BSIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948876 | 0.87 | SIGMAR1 (0.43) | ITGB3ITGA2BSIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948708 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL8948637 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL8948632 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL8948663 | 0.86 | L3MBTL1 (0.49) | ITGB3ITGA2BSIGMAR1GRM2L3MBTL1 | |
| SCHEMBL8948589 | 0.86 | L3MBTL1 (0.49) | ITGB3ITGA2BSIGMAR1GRM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |