SCHEMBL8948832

SCHEMBL8948832

Cc1cc(C)c(-c2c(C)cc(C)c3cc4ccccc4cc23)c2c1Cc1ccccc1C2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.39
CES1 P23141 2/20 0.37
BCHE P06276 1/20 0.37
ALDH1A1 P00352 5/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CASP6 P55212 2/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAP3K9 P80192 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948826 0.88 MAOA (0.50) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL9053359 0.79
SCHEMBL6903907 0.73 MAOA (0.53) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL10756250 0.70 MAOA (0.55) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL8155678 0.68 MAP3K9 (0.38) MAOACES1BCHEALDH1A1KMT2A
SCHEMBL8163015 0.67 MAP3K9 (0.41) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL6900208 0.67 MAOA (0.55) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL6906767 0.67 MAOA (0.55) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL769935 0.67 MAOA (0.50) MAOACES1BCHEALDH1A1CYP1A2
Anthrone SCHEMBL28776613 0.67 MAOA (0.78) MAOACES1BCHEALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2686045-A2 DETECTION OF MECHANICAL STRESS ON COATED ARTICLES SiO2 Medical Products, Inc. (US) 2014-01-22 EP claimed
WO-2012125736-A2 DETECTION OF MECHANICAL STRESS ON COATED ARTICLES SIO2 MEDICAL PRODUCTS, INC. (US) 2012-09-20 WO claimed
US-20250360368-A1 GOLF BALL HAVING COLOR-SHIFT EFFECT ACUSHNET COMPANY (US) 2025-11-27 US disclosed
US-20140069202-A1 DETECTION OF MECHANICAL STRESS ON COATED ARTICLES SIO2 MEDICAL PRODUCTS, LLC 2014-03-13 US disclosed
EP-2686045-A2 DETECTION OF MECHANICAL STRESS ON COATED ARTICLES SiO2 Medical Products, Inc. (US) 2014-01-22 EP disclosed
WO-2012125736-A2 DETECTION OF MECHANICAL STRESS ON COATED ARTICLES SIO2 MEDICAL PRODUCTS, INC. (US) 2012-09-20 WO disclosed
US-5501945-A Method of using multichromic polymers in packaging THE UNIVERSITY OF AKRON (US) 1996-03-26 US disclosed