SCHEMBL6906767

SCHEMBL6906767

Cc1cc(C)c2c(c1)C(=O)c1ccccc1C2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.55
CES1 P23141 2/20 0.47
BCHE P06276 1/20 0.47
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ELANE P08246 1/20 0.46
KMT2A Q03164 6/20 0.46
MEN1 O00255 4/20 0.46
KDM4E B2RXH2 2/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
METAP1 P53582 1/20 0.40
ACHE P22303 1/20 0.40
TTR P02766 1/20 0.40
GAA P10253 2/20 0.39
CASP6 P55212 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277979 0.86 PNMT (0.41) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL10694265 0.81 MAOA (0.61) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL6905059 0.77 MAOA (0.67) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL6900208 0.77 MAOA (0.55) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL8948826 0.77 MAOA (0.50) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL11611425 0.76 ELANE (0.51) MAOAALDH1A1SMN1; SMN2ELANEKMT2A
Anthrone SCHEMBL11617600 0.76 MAOA (0.78) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL15960871 0.75 METAP1 (0.43) MAOAALDH1A1ELANEKMT2AMEN1
Anthrone SCHEMBL28080093 0.75 ELANE (0.72) MAOACES1BCHEALDH1A1SMN1; SMN2
SCHEMBL6905673 0.74 MAOA (0.67) MAOACES1BCHEALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed