Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948619 | 0.92 | GRM2 (0.52) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948657 | 0.91 | GRM2 (0.47) | ITGB3ITGA2BGRM2SIGMAR1F10 | |
| SCHEMBL8948795 | 0.89 | GRM2 (0.46) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948876 | 0.88 | SIGMAR1 (0.43) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948767 | 0.88 | GRM2 (0.48) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948648 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BGRM2SIGMAR1F10 | |
| SCHEMBL8452361 | 0.87 | GRM2 (0.51) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8458486 | 0.87 | GRM2 (0.51) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948708 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BGRM2SIGMAR1 | |
| SCHEMBL8948637 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BGRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |