Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948619 | 0.91 | GRM2 (0.52) | GRM2ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8948834 | 0.91 | ITGB3 (0.50) | GRM2ITGB3ITGA2BSIGMAR1F10 | |
| SCHEMBL8948850 | 0.89 | GRM2 (0.44) | GRM2ITGB3ITGA2BSIGMAR1DRD4 | |
| SCHEMBL8948674 | 0.89 | GRM2 (0.46) | GRM2SIGMAR1DRD4TMEM97 | |
| SCHEMBL8948542 | 0.89 | SIGMAR1 (0.41) | GRM2ITGB3ITGA2BSIGMAR1DRD4 | |
| SCHEMBL8446291 | 0.88 | GRM2 (0.48) | GRM2ITGB3ITGA2BSIGMAR1DRD4 | |
| SCHEMBL8948682 | 0.84 | F10 (0.52) | GRM2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL8453566 | 0.83 | GRM2 (0.48) | GRM2SIGMAR1DRD4TMEM97 | |
| SCHEMBL8948708 | 0.82 | ITGB3 (0.65) | GRM2ITGB3ITGA2BSIGMAR1USP14 | |
| SCHEMBL8948637 | 0.82 | ITGB3 (0.65) | GRM2ITGB3ITGA2BSIGMAR1USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |