Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949249 | 0.94 | CNR2 (0.41) | POLBST14CNR2CNR1HPGD | |
| SCHEMBL8949281 | 0.90 | CNR2 (0.40) | POLBST14ITGB3ITGA2BCNR2 | |
| SCHEMBL8949199 | 0.90 | ITGB3 (0.43) | POLBST14ITGB3ITGA2BCNR2 | |
| Hydrochloric Acid SCHEMBL8949111 | 0.89 | ITGB3 (0.43) | POLBST14ITGB3ITGA2BCNR2 | |
| SCHEMBL8949217 | 0.89 | CNR2 (0.42) | PRSS1ST14TP53ITGB3ITGA2B | |
| SCHEMBL8949068 | 0.86 | POLB (0.41) | POLBRXFP1KMT2ATP53THRB | |
| SCHEMBL9571678 | 0.85 | CNR2 (0.40) | POLBCNR2CNR1HPGDALDH1A1 | |
| SCHEMBL8949028 | 0.82 | HPGD (0.38) | POLBCNR2CNR1HPGDALDH1A1 | |
| SCHEMBL9260471 | 0.81 | CNR2 (0.41) | POLBCNR2CNR1HPGD | |
| Hydrochloric Acid SCHEMBL8949338 | 0.81 | CNR2 (0.45) | PRSS1PRSS2PRSS3PLGST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |