Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949249 | 0.91 | CNR2 (0.41) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL8949281 | 0.90 | CNR2 (0.40) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL8948967 | 0.89 | POLB (0.47) | CNR2CNR1ALDH1A1HPGDTP53 | |
| SCHEMBL8949199 | 0.88 | ITGB3 (0.43) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| Hydrochloric Acid SCHEMBL8949111 | 0.88 | ITGB3 (0.43) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL9571678 | 0.82 | CNR2 (0.40) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL8949028 | 0.78 | HPGD (0.38) | CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL9260471 | 0.78 | CNR2 (0.41) | CNR2CNR1HPGD | |
| Hydrochloric Acid SCHEMBL8949338 | 0.78 | CNR2 (0.45) | CNR2CNR1HPGDF2F10 | |
| SCHEMBL8949242 | 0.78 | POLB (0.39) | ALDH1A1HPGDUSP2TP53ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |