Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 15/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571678 | 0.94 | CNR2 (0.40) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8949249 | 0.87 | CNR2 (0.41) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8949068 | 0.87 | POLB (0.41) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8948967 | 0.82 | POLB (0.47) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL9260471 | 0.82 | CNR2 (0.41) | HPGDPOLBCNR2CNR1 | |
| SCHEMBL8949199 | 0.79 | ITGB3 (0.43) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8949281 | 0.79 | CNR2 (0.40) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8949217 | 0.78 | CNR2 (0.42) | HPGDCNR2CNR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8949111 | 0.78 | ITGB3 (0.43) | HPGDPOLBCNR2CNR1ALDH1A1 | |
| SCHEMBL8948977 | 0.77 | FAAH (0.41) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |