Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949088 | 0.99 | TMPRSS15 (0.44) | TMPRSS15ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949291 | 0.87 | TMPRSS15 (0.46) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8949052 | 0.73 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL397363 | 0.71 | WDR5 (0.56) | PKMNQO2 | |
| SCHEMBL8949306 | 0.70 | ITGB3 (0.46) | TMPRSS15ITGB3ITGA2BNPC1USP2 | |
| SCHEMBL8949315 | 0.70 | ITGB3 (0.46) | TMPRSS15ITGB3ITGA2BNPC1USP2 | |
| SCHEMBL8886607 | 0.70 | ITGB3 (0.57) | TMPRSS15ITGB3ITGA2BNQO2 | |
| SCHEMBL8949364 | 0.70 | F10 (0.41) | NPC1USP2TP53PKMRAB9A | |
| SCHEMBL8886144 | 0.67 | ITGB3 (0.54) | TMPRSS15ITGB3ITGA2BNQO2 | |
| SCHEMBL9253978 | 0.67 | ITGB3 (0.37) | TMPRSS15ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |