Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709264 | 0.84 | MEN1 (0.63) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20363245 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9334060 | 0.80 | MEN1 (0.58) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9334064 | 0.80 | MEN1 (0.58) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20363332 | 0.78 | MEN1 (0.54) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL7767276 | 0.77 | MEN1 (0.63) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL12519203 | 0.75 | CNR2 (0.79) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20363313 | 0.75 | ALDH1A1 (0.60) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL8447183 | 0.75 | CYP2A6 (0.51) | CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL196487 | 0.74 | KMT2A (0.70) | MEN1KMT2ACYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |