SCHEMBL894922

SCHEMBL894922

O=C(Cl)c1ccccc1/C=C/c1ccccc1C(=O)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 2/20 0.52
BCHE P06276 1/20 0.42
GUSB P08236 1/20 0.42
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GRIK1 P39086 1/20 0.39
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA3 P42263 1/20 0.39
GRIA4 P48058 1/20 0.39
GRIK2 Q13002 1/20 0.39
GRIK3 Q13003 1/20 0.39
NFKB1 P19838 3/20 0.39
NFE2L2 Q16236 2/20 0.39
JUN P05412 1/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31634301 0.90 TRPA1 (0.52) ALDH1A1ALOX15BCHEGRIK1GRIA1
SCHEMBL25139607 0.87 ALDH1A1 (0.45) ALDH1A1ALOX15BCHEGUSBCES2
SCHEMBL9879643 0.87 ALDH1A1 (0.45) ALDH1A1ALOX15BCHEGUSBCES2
Hydrochloric Acid SCHEMBL27463346 0.86 ALDH1A1 (0.44) ALDH1A1ALOX15BCHEGUSBCES2
SCHEMBL30587401 0.85 HDAC1 (0.43) ALDH1A1ALOX15GRIK1GRIA1GRIA2
SCHEMBL7536432 0.84 LMNA (0.52) ALDH1A1ALOX15BCHEGUSBCES2
SCHEMBL29951511 0.84 LMNA (0.52) ALDH1A1ALOX15BCHEGUSBCES2
SCHEMBL31157042 0.84 NPC1 (0.53) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL2726869 0.82 MAOB (0.50) ALDH1A1ALOX15BCHEMAPTTDP1
SCHEMBL28836884 0.82 ALDH1A1 (0.41) ALDH1A1ALOX15BCHEGUSBNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2498136-B1 Intermediate transfer belt and image forming apparatus using the same RICOH CO LTD (JP) 2018-05-02 EP disclosed
US-8521073-B2 Intermediate transfer member and image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2013-08-27 US disclosed
US-20120230740-A1 INTERMEDIATE TRANSFER BELT AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY, LTD. (JP) 2012-09-13 US disclosed
EP-2498136-A1 Intermediate transfer belt and image forming apparatus using the same Ricoh Company, Ltd. (JP) 2012-09-12 EP disclosed
US-20120082488-A1 INTERMEDIATE TRANSFER MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY, LTD. (JP) 2012-04-05 US disclosed
EP-0583888-B2 Water-dispersible UV light-absorbing copolymer UNILEVER PLC (GB) 2001-01-17 EP disclosed
EP-0583888-A1 Water-dispersible UV light-absorbing copolymer UNILEVER PLC (GB) 1994-02-23 EP disclosed