Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949242 | 1.00 | POLB (0.39) | POLBUSP2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9571672 | 0.92 | ITGB3 (0.38) | POLBUSP2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9571670 | 0.92 | ITGB3 (0.38) | POLBUSP2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8949249 | 0.87 | CNR2 (0.41) | POLBALDH1A1SMN1; SMN2HPGDF2 | |
| Hydrochloric Acid SCHEMBL8948990 | 0.83 | F10 (0.34) | POLBSMN1; SMN2HPGDITGB3ITGA2B | |
| SCHEMBL8949284 | 0.82 | F2 (0.38) | ITGB3ITGA2BTMPRSS15F2 | |
| SCHEMBL8949279 | 0.82 | F2 (0.38) | ITGB3ITGA2BTMPRSS15F2 | |
| Hydrochloric Acid SCHEMBL8949003 | 0.81 | F2 (0.37) | ITGB3ITGA2BTMPRSS15F2 | |
| SCHEMBL8948967 | 0.81 | POLB (0.47) | POLBKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8949166 | 0.79 | F2 (0.38) | POLBUSP2KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |