Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949284 | 1.00 | F2 (0.38) | F2F10TMPRSS15ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949003 | 0.99 | F2 (0.37) | F2F10TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8949134 | 0.90 | ITGB3 (0.38) | F2F10ITGB3ITGA2BBRD4 | |
| SCHEMBL8949140 | 0.90 | ITGB3 (0.38) | F2F10ITGB3ITGA2BBRD4 | |
| SCHEMBL8949034 | 0.84 | CFTR (0.42) | F2F10TMPRSS15PLGPRSS1 | |
| SCHEMBL8949131 | 0.84 | CFTR (0.42) | F2F10TMPRSS15PLGPRSS1 | |
| SCHEMBL8949158 | 0.82 | EGLN1 (0.34) | EGLN1PDE10AHRH3 | |
| Hydrochloric Acid SCHEMBL8948990 | 0.82 | F10 (0.34) | F2F10TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8949242 | 0.82 | POLB (0.39) | F2TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8949244 | 0.82 | POLB (0.39) | F2TMPRSS15ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | claimed |
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |