Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949056 | 1.00 | CNR2 (0.41) | CNR2CNR1CFTRKLK7HPGD | |
| SCHEMBL8948977 | 0.93 | FAAH (0.41) | CNR2CNR1CFTRFAAHMEN1 | |
| SCHEMBL8949034 | 0.89 | CFTR (0.42) | CNR2CNR1CFTRKLK7HPGD | |
| SCHEMBL8949131 | 0.89 | CFTR (0.42) | CNR2CNR1CFTRKLK7HPGD | |
| SCHEMBL8949141 | 0.83 | EGLN1 (0.45) | CNR2CNR1CFTRKLK7MEN1 | |
| SCHEMBL8949256 | 0.83 | EGLN1 (0.45) | CNR2CNR1CFTRKLK7MEN1 | |
| SCHEMBL8949262 | 0.83 | EGLN1 (0.45) | CNR2CNR1CFTRKLK7MEN1 | |
| SCHEMBL9571678 | 0.82 | CNR2 (0.40) | CNR2CNR1CFTRHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8949162 | 0.82 | CNR2 (0.46) | CNR2CNR1CFTRKLK7MEN1 | |
| SCHEMBL8949148 | 0.80 | CNR2 (0.46) | CNR2CNR1KLK7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |